Camptothecin

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Camptothecin Specification

Molecular Weight
348.35 g/mol

Poisonous
YES

Storage
Store in a cool dry place under inert atmosphere

Smell
Odorless

Shelf Life
2 Years if properly stored

Boiling point
Not Applicable

EINECS No
231-710-0

Structural Formula
Not Specified

Taste
Not Applicable

Heavy Metal (%)
20 ppm

Particle Size
Not Specified

Color
Pale Yellow

Melting Point
264C

HS Code
29329990

Solubility
Slightly soluble in methanol and DMSO

Loss on Drying
0.5%

Ph Level
Not Applicable

Molecular Formula
C20H16N2O4

Medicine Name
Camptothecin

Chemical Name
Camptothecin

CAS No
7689-03-4

Type
Alkaloid

Grade
Pharmaceutical Grade

Usage
Used in cancer treatment as a precursor for anticancer drugs like irinotecan and topotecan

Purity(%)
98%

Appearance
Crystalline Powder

Physical Form
Solid

About Camptothecin

We have carved a reputed niche in the industry, for formulating and supplying Camptothecin Powder. It is isolated from the stem wood of Camptotheca acuminate tree. This compound is known to have chemical formula C20H16N2O4 and molar mass of 348.358 g/mol. It works by inhibiting DNA Topoisomerase I, resulting in prevention of DNA re-ligation which causes apoptosis. Camptothecin Powder is an anti-cancerous agent which finds it use for metastatic colon or rectal cancer.

Features:

It is an alkaloid
Administered intravenously
Has melting point of 275 to 277 degrees Celsius

Applications in Oncology

Camptothecin is notable for its role in the development of innovative anticancer therapies. Pharmaceutical companies use it as a foundational compound to synthesize irinotecan and topotecan, which inhibit DNA replication in cancer cells. Its efficacy has contributed significantly to the advancement of cancer treatment protocols worldwide.

Safe Handling and Storage Guidelines

Given its poisonous nature and pharmaceutical grade, Camptothecin requires stringent safety measures during handling and storage. It should be kept in a cool, dry spot, shielded with inert gases to maintain stability and prevent deterioration. Protective gear and proper ventilation are recommended for personnel managing this compound.

FAQs of Camptothecin:

Q: What is Camptothecin used for in the pharmaceutical industry?

A: Camptothecin is primarily utilized as a precursor in the synthesis of anticancer drugs like irinotecan and topotecan. These medications are essential in the treatment of various cancers, especially colon and ovarian cancers.

Q: How should Camptothecin be stored to ensure its efficacy?

A: It should be stored in a cool, dry place under inert atmosphere to preserve its stability and effectiveness. Avoid exposure to moisture, light, and air to maintain its pharmaceutical quality.

Q: When is Camptothecin considered suitable for use based on its shelf life?

A: Camptothecin remains suitable for use within 2 years of purchase, provided it is stored correctly as per recommended conditions, which helps ensure its purity and potency.

Q: Where is Camptothecin commonly exported, imported, and manufactured?

A: Camptothecin is traded globally and is notably manufactured, exported, and supplied by companies based in India, where stringent pharmaceutical standards are maintained.

Q: What precautions must be observed during the handling of Camptothecin?

A: Due to its poisonous nature, handlers must wear protective equipment, such as gloves and safety goggles, and work in well-ventilated environments to minimize exposure risks.

Q: How does Camptothecin benefit cancer treatment protocols?

A: As a precursor for drugs inhibiting DNA replication, Camptothecin plays a crucial role in targeting and destroying cancer cells, thus enhancing the effectiveness of chemotherapy regimens.

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